The Comparison of Degradation Time, Weight Loss and Surface Fibrin Structure Between Gauze-Compression and Heat-Compression Platelet-Rich Fibrin Membrane

Objective: To evaluate the effect of heat-compression to platelet-rich fibrin (PRF) membrane in degradation time, weight loss and to examine surface fibrin structure using scanning electron microscope (SEM).

Methods: Sixty PRF membranes that were prepared from human blood (ten healthy volunteers). Samples were compressed at various temperatures and were arranged into six groups: control (room temperature), 60, 70, 80, 90 and 100°C. Nine of the ten samples from each group were evaluated for their degradation time and weight loss. One remaining sample was examined the surface fibrin structure using SEM.

Results: The 90 and 100°C groups had significantly different degradation times compared to those in the control, 60 and 70°C groups (p<0.05). There was no significant difference in the mean weight percentage among the six groups on each day (p<0.05). But when compared among the days in the same group, the 90 and 100°C groups were significantly different in the early phase to 11 and 6 days, respectively. The surface fibrin structure in the 90 and 100°C groups showed the least interfibrous space and lowest porosity.

Conclusions: The 90 and 100°C groups had significantly longer degradation times and delayed the early stage of degradation. It might be applied in surgical operations that need PRF membrane stability in the early phase.

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Charanthanyakun N, Tachasuttirut K, Permpanich P, Kaewkumnert S, Powcharoen W. The Comparison of Degradation Time, Weight Loss and Surface Fibrin Structure Between Gauze-Compression and Heat-Compression Platelet-Rich Fibrin Membrane: Original articles. CM Dent J [Internet]. 2020 Jul 14 [cited 2024 Jul 15];41(2):75-87. Available from: https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=55

Charanthanyakun, N., Tachasuttirut, K., Permpanich, P., Kaewkumnert, S. & Powcharoen, W. (2020). The Comparison of Degradation Time, Weight Loss and Surface Fibrin Structure Between Gauze-Compression and Heat-Compression Platelet-Rich Fibrin Membrane. CM Dent J, 41(2), 75-87. Retrieved from: https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=55

Charanthanyakun, N., Tachasuttirut Kathawut,Permpanich Piyanuj,Kaewkumnert Sahatut and Powcharoen Warit. 2020. "The Comparison of Degradation Time, Weight Loss and Surface Fibrin Structure Between Gauze-Compression and Heat-Compression Platelet-Rich Fibrin Membrane." CM Dent J, 41(2), 75-87. https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=55

Charanthanyakun, N. et al. 2020. 'The Comparison of Degradation Time, Weight Loss and Surface Fibrin Structure Between Gauze-Compression and Heat-Compression Platelet-Rich Fibrin Membrane', CM Dent J, 41(2), 75-87. Retrieved from https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=55

Charanthanyakun, N., Tachasuttirut, K., Permpanich, P., Kaewkumnert, S. and Powcharoen, W. "The Comparison of Degradation Time, Weight Loss and Surface Fibrin Structure Between Gauze-Compression and Heat-Compression Platelet-Rich Fibrin Membrane", CM Dent J, vol.41, no. 2, pp. 75-87, Jul. 2020.

Charanthanyakun, N., Tachasuttirut, K., Permpanich, P., et al. "The Comparison of Degradation Time, Weight Loss and Surface Fibrin Structure Between Gauze-Compression and Heat-Compression Platelet-Rich Fibrin Membrane." CM Dent J, vol.41, no. 2, Jul. 2020, pp. 75-87, https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=55