Effect of Dental Fluorosis on Orthodontic Bond Strength: A Review of the Literature

Dental fluorosis is the hypomineralization of the enamel caused by continuous ingestion of excessive fluoride during enamel formation. Fluorosed enamel is characterized by an outer hypermineralized, acid resistant layer, and by the formation of more porous enamel in the area of the subsurface hypomineralization. The etching pattern of fluorsoed enamel has less irregularity than that of normal enamel. Orthodontists face difficulties in bonding brackets to fluorotic teeth. There are two bonding systems for bonding brackets to fluorotic teeth: total-etching and selfetching bonding systems. The effectiveness of bonding to fluorotic teeth is controversial. The purposes of this review article are to describe dental fluorosis in terms of clinical appearance, incidence, classification and etching pattern of fluorosed enamel, and to describe and compare the bond strength of total-etching and self-etching bonding systems when used to bond brackets to fluorotic teeth.

1. DenBesten PK, Thariani H. Biological mechanisms of fluorosis and level and timing of systemic exposure to fluoride with respect to fluorosis. J Dent Res 1992; 71: 1238-1243.

2. Kidd EA. Fluoride supplement. Essentials of dental caries the disease and its mangement. 1st ed. Narayana:Blackwell Munkgaard 2005: 109-125.

3. Vuttipitayamongkol C. Decentralization and community participation in dealing with fluorosis in Lampang province, Thailand. Proceeding of the 3rd international workshop on fluorosis prevention and defluoridation water 2002: 120-124.

4. Adanir N, Türkkahraman H, Yalcin Güngör A. Effects of adhesion promoters on the shear bond strengths orthodontic brackets to fluorosed enamel. Eur J Orthod 2009;31: 276- 280.

5. Juntharavijit S. Report of study. Report of The risk builds the health from receiving fluoride 2003: 7-12.

6. Miller RA. Bonding fluorosed teeth: new materials for old problems. J Clin Orthod 1995; 29: 424-427.

7. Opinya GN, Pameijer CH. Tensile bond strength of fluorosed Kenyan teeth using the acid etch technique. Int Dent J 1986;36: 225- 229.

8. Ng’ang’a PM, Ogaard B, Cruz R, Chindia ML, Aasrum E. Tensile strength of orthodontic brackets bonded directly to fluorotic and nonfluorotic teeth: an in vitro comparative study. Am J Orthod Dentofacial Orthop 1992; 102: 244-250.

9. Ateyah N, Akpata E. Factors affecting shear bond strength of composite resin to fluorosed human enamel. Oper Dent 2000; 25: 216-222.

10. Weerasinghe DS, Nikaido T, Wettasinghe KA, Abayakoon JB, Tagami J. Micro-shear bond strength and morphological analysis of a selfetching primer adhesive system to fluorosed enamel. J Dent 2005; 33: 419-426.

11. Adanir N, Türkkahraman H, Güngör AY. Effects of Fluorosis and Bleaching on Shear Bond Strengths of Orthodontic Brackets. Eur J Dent 2007; 1: 230-235.

12. Murray JJ, Rugg-Gunn AJ, Jenkins GN. Fluorides in caries prevention. 3rd ed. Cambridge: Butterworth-Heinemann; 1991: 324- 336.

13. Yanagisawa T, Takuma S, Fejerskov O. Ultrastructure and composition of enamel in human dental fluorosis. Adv Dent Res 1989; 3: 203-210.

14. Ng F, Manton DJ. Aesthetic management of severely fluorosed incisors in an adolescent female. Aust Dent J 2007; 52: 243-248.

15. Thylstrup A, Fejerskov O. Clinical appearance of dental fluorosis in permanent teeth in relation to histologic changes. Community Dent Oral Epidemiol 1978; 6: 315-328.

16. Wenzel A, Thystrup A, Melsen B, Fejerskov O. The relationship between water-born fluoride, dental fluorosis and skeletal development in 11-15 year old Tanzanian girls. Arch Oral Biol 1982; 27: 1007-1011.

17. Murray JJ, Rugg-Gunn AJ, Jenkins GN. Fluorides in caries prevention. 3rd ed. Cambridge: Butterworth-Heinemann; 1991: 222- 261.

18. National Research Council (NRC). Health effects of ingested fluoride. Washington, D.C.: National academy press 1993.

19. Noppakun W, Ratanasthein B, Prapamontol T, Asanchinda P, Obsuwan K, Na Suwna J,Promputha. Occurence of fluorosis due to Geothermal Sources in a Northern Thailand Subdistrict. 3rd international workshop on fluorosis prevention and defluoridation of water 2002: 22-29.

20. Horowitz HS. Indexes for measuring dental fluorosis. J Public Health Dent 1986; 46: 179- 183.

21. Fejerskov O, Manji F, Baelum V. The nature and mechanisms of dental fluorosis in man. J Dent Res 1990; 69: 692-701.

22. Buonocore MG. A simple method of increasing the adhesion of acrylic filling materials to enamel surfaces. J Dent Res 1955; 34: 849-853.

23. Newman GV, Snyder WH, Wilson CE, Jr. Acrylic adhesives for bonding attachments to tooth surfaces. Angle Orthod 1968; 38: 12-18.

24. Retief DH, Dreyer CJ, Gavron G. The direct bonding of orthodontic attachments to teeth by means of an epoxy resin adhesive. Am J Orthod 1970; 58: 21-40.

25. Newman GV. Epoxy adhesives for orthodontic attachments: progress report. Am J Orthod 1965; 51: 901-912.

26. Ermis RB, De Munck J, Cardoso MV, Coutinho E, Van Landuyt KL, Poitevin A et al. Bonding to ground versus unground enamel in fluorosed teeth. Dent Mater 2007; 23: 1250- 1255.

27. Ertugrul F, Turkun M, Turkun LS, Toman M, Cal E. Bond strength of different dentin bonding systems to fluorotic enamel. J Adhes Dent 2009; 11: 299-303.

28. Ratnaweera PM, Nikaido T, Weerasinghe D, Wettasinghe KA, Miura H, Tagami J. Microshear bond strength of two all-in-one adhesive systems to unground fluorosed enamel. Dent Mater J 2007; 26: 355-360.

29. Güngör AY, Türkkahraman H, Adanir N, Alkis H. Effects of fluorosis and self etching primers on shear bond strengths of orthodontic brackets. Eur J Dent 2009; 3: 173-177.

30. Shida K, Kitasako Y, Burrow MF, Tagami J. Micro-shear bond strengths and etching efficacy of a two-step self-etching adhesive system to fluorosed and non-fluorosed enamel. Eur J Oral Sci 2009;117:182-186.

31. Proffit WR. Contemporary orthodontic. 3rd ed. St. Louis: Mosby ; 2000: 397.

32. Ten Cate AR. Oral histology : development, structure, and function 5th ed. St. Louis: Mosby; 1998: 218-235.

33. Richards A, Fejerskov O, Baelum V. Enamel fluoride in relation to severity of human dental fluorosis. Adv Dent Res 1989; 3: 147-153.

34. Kochavi D, Gedalia I, Anaise J. Effect of conditioning with fluoride and phosphoric acid on enamel surfaces as evaluated by scanning electron microscopy and fluoride incorporation. J Dent Res 1975; 54: 304-309.

35. Al-Sugair MH, Akpata ES. Effect of fluorosis on etching of human enamel. J Oral Rehabil 1999; 26: 521-528.

36. Fejerskov O, Manji F, Baelum V. Dental fluorosis-a handbook for health workers. 1st. ed. Copenhagen; Munksgarrd 1988: 11-50.

37. Reynold JR. A review of direct orthodontic bonding. Br J Orthod 1975; 2: 171-178.

38. Noble J, Karaiskos NE, Wiltshire WA. In vivo bonding of orthodontic brackets to fluorosed enamel using an adhesion promotor. Angle Orthod 2008; 78: 357-360.

39. Nakabayashi N, Kojima K, Masuhara E. The promotion of adhesion by the infiltration of monomers into tooth substrates. J Biomed Mater Res 1982; 16: 265-273.

40. Hotta K, Mogi M, Miura F, Nakabayashi N. Effect of 4-MET on bond strength and penetration of monomers into enamel. Dent Mater 1992; 8: 173-175.

41. Duan Y, Chen X, WU j. Clinical composition of bond failures using different enamel preparations of severely fluorotic teeth. J Clin Orthod 2006: 152-154.

Chotikaew K, Patanaporn V. Effect of Dental Fluorosis on Orthodontic Bond Strength: A Review of the Literature: Review articles. CM Dent J [Internet]. 2024 Dec 04 [cited 2025 May 02];32(1):39-48. Available from: https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=357

Chotikaew, K. & Patanaporn, V. (2024). Effect of Dental Fluorosis on Orthodontic Bond Strength: A Review of the Literature. CM Dent J, 32(1), 39-48. Retrieved from: https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=357

Chotikaew, K., and Virush Patanaporn. 2024. "Effect of Dental Fluorosis on Orthodontic Bond Strength: A Review of the Literature." CM Dent J, 32(1), 39-48. https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=357

Chotikaew, K. et al. 2024. 'Effect of Dental Fluorosis on Orthodontic Bond Strength: A Review of the Literature', CM Dent J, 32(1), 39-48. Retrieved from https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=357

Chotikaew, K. and Patanaporn, V. "Effect of Dental Fluorosis on Orthodontic Bond Strength: A Review of the Literature", CM Dent J, vol.32, no. 1, pp. 39-48, Dec. 2024.

Kittinunt Chotikaew, Virush Patanaporn "Effect of Dental Fluorosis on Orthodontic Bond Strength: A Review of the Literature." CM Dent J, vol.32, no. 1, Dec. 2024, pp. 39-48, https://www.dent.cmu.ac.th/cmdj/frontend/web/?r=site/viewarticle&id=357