Effect of Casein Phosphopeptide-Amorphous Calciumphosphate on Bond Strength of Dental Adhesives
Today’ s dental practice trend is minimal intervention instead of extensive restorative procedure. Recently, casein phosphopeptideamorphous calcium phosphate (CPP-ACP) has become popular because it increases the level of calcium phosphate in dental plaque, preventing demineralization, enhancing remineralization, reducing the adherence of Streptococcus mutans and enhancing the effect of fluoride. CPP-ACP is now commercially available in dental products in several forms, such as topical anesthetic paste, toothpaste, mouth rinse and chewing gum. Moreover, CPP-ACP can be added to glass-ionomer restorative materials and zinc oxide non-eugenol temporary luting cements and ACP can be added as a bioactive filler in resin composite. It is necessary to determine if the material containing CPP-ACP can release calcium and phosphate ions without adversely affecting the setting reaction, physical properties and usability of these materials Otherwise, the presence of CPP-ACP on the dentin surface may decrease the bonding effectiveness of dental adhesive system due to the increasing of dentin surface hardness, and may contribute to the success or failure of resin composite restorations.
1. Mount GR, Ngo H. Minimal intervention: A new concept for operative dentistry. Quintessence Int 2000; 31: 527-533.
2. Peter M. Strategies for noninvasive demineralized tissue repair. Dent Clin North Am 2010; 54: 507-525.
3. Zeno DM. Dental caries process. Dent Clin North Am 1999; 43: 635-664.
4. Ten Cate JM. Current concepts on the theories of the mechanism of action of fluoride. Acta Odontal Scand 1999; 57: 325-329.
5. Rose RK, Effect of anticariogenic casein phosphopeptide on calcium diffusion in streptococcal model dental plaque. Arch Oral Biol 2000; 45: 569-575.
6. Iijima Y, Cai F, Shen P, Walker G, Reynolds C, Reynolds EC. Acid resistance of enamel subsurface lesions by sugar-free chewing gum containing casein phosphopeptide-amorphous calcium phosphate. Caries Res 2004; 38: 551- 556.
7. Cochrance NJ, Saranathan S, Cai F, Cross KJ, Reynolds EC. Enamel subsurface lesion remineralization with casein phosphopeptide stabilized solutions of calcium, phosphate and fluoride. Caries Res 2008; 42: 88-97.
8. Termine JD, Peckauskas RA, Posner AS. Calcium phosphate formation in vitro. Arch Biochem Biophys 1970; 140: 318-325.
9. Reynolds EC. Anticariogenic complexes of amorphous calcium phosphate stabilized by casein phosphopeptides: A review. Spec Care Dentist 1998; 18: 8-16.
10. Reynolds EC, Chain CJ, Webber FL. Anticariogenicity of calcium phosphate complexes of tryptic casein phosphopeptides in the rat. J Dent Res 1995; 74: 1272-1279.
11. Reynolds EC, Black CL, Cai F. Advances in enamel remineralization: anticariogenic casein phosphopeptide-amorphous calcium phosphate. J Clin Dent 1999; 10: 86-88.
12. Adebayo OA, Burrow MF, Tyas MJ. Effects of conditioners on micro-shear bond strength to enamel after carbamide peroxide bleaching and/or casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) treatment. J Dent 2007; 35: 861-870.
13. Van Landuyt KL, Kanumilli P, De Munck J, Peumans M, Lambrechts, Van Meerbeek B. Bond strength of a mild self-etch adhesive with and without prior acid etching. J Dent 2006; 34:77-85.
14. Sattabanasuk V, Burrow MF, Yasushi S, Tagami J. Resin bonding to dentine after casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) treatments. J Adhes Sci Technol 2009; 23: 1149-1161.
15. Adebayo OA, Burrow MF, Tyas MJ. Dentine bonding after CPP-ACP paste treatment with and without conditioning. J Dent 2008; 36: 1013-1024.
16. Es-Souni M, Fischer BH, Zaporojshenko V. On the interaction of polyacrylic acid as a conditioning agent with bovine enamel. Biomaterials 2002; 23: 2871-2878.
17. Tay FR, SmalesRJ, Ngo H, Wei SH, Pashley DH. Effect of different conditioning protocols on adhesion of a GIC to dentin. J Adhes Dent 2001; 3: 153-167.
18. Antonucci JM, O’ Donnell JNR, Schumacher GE, Skrtic D. Amorphous calcium phosphate composites and their effect on compositeadhesive-dentin bonding. J Adhes Sci Technol 2009; 23: 1133-1147.
19. Skrtic D, Antonucci JM. Dental composites based on amorphous calcium phosphate-resin composite/ physicochemical properties study. J Biomater Appl 2007; 21: 375-393.
20. Schumacher GE, Antonucci JM, O’ Donnell JNR, Skrtic D. The use of amorphous calcium phosphate composites as bioactive basing materials: Their effect on the strength of the composite/adhesive/ dentin bond. J Am Dent Assoc 2007; 138: 1476-1484.
21. Eanes ED, Gillessen IH, Posner AS. Intermediate states in the precipitation of hydroxyapatite. Nature 1965; 208: 365-367.
22. Skrtic D, Antonucci JM, Eanes ED, Eidelman N. Dental composites based on hybrid and surface-modified amorphous calcium phosphates. Biomaterials 2004; 25: 1141-1150.
23. Srinivasan N, Kavitha M, Loganathan S. Comparison of the remineralization potential of CPP-ACP and CPP-ACP with 900 ppm fluoride on eroded human enamel: An in situ study. Arch Oral Biol 2010 Jul; 55: 541-544.
24. Grant LP, Thompson A, Tanzer JM. Caries inhibition in rats by a remineralizing toothpaste. J Clin Dent 1999; 10: 30-33.
25. Kaufman HW, Wolff MS, Winston AE, Ttriol CW. Clinical evaluation of the effect of a remineralizing toothpaste on dentinal sensitivity. J Clin Dent 1999; 10: 50-54.
26. Jane MC. Minimal Intervention Dentistry: Part1. Strategies for addressing the new caries challenge in older patients. J Can Dent Assoc 2006; 72: 427-433.
27. Lata S, Varghese N, Varughese J. Remineralization potential of fluoride and amorphous calcium phosphate-casein phosphopeptide on enamel lesions: An in vitro comparative evaluation. J Conserv Dent 2010; 13: 42-46.
28. Mazzaoui SA, Burrow MF, Tyas MJ, Cashper SG, Eakins D, Reynolds EC. Incorporation of casein phosphopeptide-amorphous calcium phosphate into a glass-ionomer cement. J Dent Res 2003; 82: 914-918.
29. Moezizadeh M, Moayedi S. Anticariogenic Effect of amorphous calcium phosphate stabilized by casein phosphopeptide: A review article. Res J Bio Sci 2009; 4: 132-136.
30. Wong RH, Wilson PR. The effect of seating force and die spacing on pulpward cementation pressure transmission:a laboratory study. Int Dent J 1997; 47: 45-52.
31. Wong RH, Palamara JE, Wilson PR, Reynolds EC, Burrow MF. Effect of CPP-ACP addition on physical properties of zinc oxide noneugenol temporary cements. Dent Mater 2011; 27(4): 329-338.
32. Hiraishi N, Kitasako Y, Nikaido T, Foxton RM, Tagami J, Nomura S. Acidity of conventional luting cements and their diffusion through bovine dentin. Int Endod J 2003; 36: 622-628.