Sealing Ability of Root Canal Filling in Canals Medicated with 3Mix-MP
There has been a more tendency to use 3Mix-MP as intracanal medication because of its efficiency to eliminate bacteria remaining in endodontic lesion. However, Macrogol; which is a composition of vehicle may cause remnant of the medication in root canal and may affect on sealing ability of root canal fillings. The purpose of this study was to evaluate the sealing ability of root canal filling in canals medicated with 3MixMP. Extracted ninety-two human upper incisors were prepared and randomly divided into two groups. Group 1 was medicated with 3Mix-MP. Group 2 was not medicated. After irrigation, two teeth of each group were examined with SEM. The others were obturated with gutta percha and either AH plus or ZOE sealer. The specimens were subjected to leakage study using dye penetration method. Results showed that canals medicated with 3Mix-MP had significantly more leakage than those without medication in canals sealed with AH plus (P < 0.05). However, there was no significantly difference of leakage among canals sealed with ZOE sealer
1. Kakehashi S, Stanley HR, Fitzgerald RJ. The effects of surgical exposures of dental pulps in germ-free and conventional laboratory rats. Oral Surgery, Oral Medicine, Oral Pathology. 1965; 20: 340-49.
2. Bystrom A, Sundqvist G. Bacteriologic evaluation of the efficacy of mechanical root canal instrumentation in endodontic therapy. Scand J Dent Res. 1981; 89: 321-8.
3. Evans M, Davies JK, Sundqvist G, Figdor D. Mechanisms involved in the resistance of Enterococcus faecalis to calcium hydroxide. Int Endod J. 2002; 35: 221-8.
4. Takushige T, Cruz EV, Asgor Moral A, Hoshino E. Endodontic treatment of primary teeth using a combination of antibacterial drugs. Int Endod J. 2004; 37: 132-8.
5. Hoshino E, Kurihara-Ando N, Sato I, Uematsu H, Sato M, Kota K, et al. In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. Int Endod J. 1996; 29: 125-30.
6. Cruz EV, Kota K, Huque J, Iwaku M, Hoshino E. Penetration of propylene glycol into dentine. Int Endod J. 2002; 35: 330-6.
7. Alam T. Susceptibility of Enterococus faecalis to a Combination of Antibacterial Drugs (3Mix) in vitro. Journal Oral Biosci. 2005; 47: 315-20.
8. Iwaya SI, Ikawa M, Kubota M. Revascularization of an immature permanent tooth with apical periodontitis and sinus tract. Dent Traumatol. 2001; 17: 185-7.
9. Trope M. Regenerative potential of dental pulp. J Endod. 2008; 34: S13-7.
10. Windley W, Teixeira F, Levin L, Sigurdsson A, Trope M. Disinfection of immature teeth with a triple antibiotic paste. J Endod. 2005; 31: 439-43.
11. Ozan U, Kursat E. Endodontic treatment of a large cyst-like periradicular lesion using a combination of antibiotic drugs: a case report. Journal of Endodontics. 2005; 31: 898-900.
12. Crump M. Differential diagnosis in endodontic failure. Dent Clin North Am. 1979; 23: 617-35.
13. Ingle J, Newton C, West J. Obturation of the radicular space. Fifth ed. Hamilton London: BC Decker Inc 2002.
14. Hosoya N, Kurayama H, Iino F, Arai T. Effects of calcium hydroxide on physical and sealing properties of canal sealers. Int Endod J. 2004; 37: 178-84.
15. Lambrianidis T, Margelos J, Beltes P. Removal efficiency of calcium hydroxide dressing from the root canal. J Endod. 1999; 25: 85-8.
16. Verissimo DM, do Vale MS. Methodologies for assessment of apical and coronal leakage of endodontic filling materials: a critical review. J Oral Sci. 2006; 48: 93-8.
17. Camps J, Pashley D. Reliability of the dye penetration studies. J Endod. 2003; 29: 592-4.
18. Pommel L, Camps J. Effects of pressure and measurement time on the fluid filtration method in endodontics. J Endod. 2001; 27: 256-8.
19. Maltezos C, Glickman GN, Ezzo P, He J. Comparison of the sealing of Resilon, Pro Root MTA, and Super-EBA as root-end filling materials: a bacterial leakage study. J Endod. 2006; 32: 324-7.
20. Schafer E, Olthoff G. Effect of three different sealers on the sealing ability of both thermafil obturators and cold laterally compacted GuttaPercha. J Endod. 2002; 28: 638-42.
21. Economides N, Liolios E, Kolokuris I, Beltes P. Long-term evaluation of the influence of smear layer removal on the sealing ability of different sealers. J Endod. 1999; 25: 123-5.
22. Gettleman BH, Messer HH, ElDeeb ME. Adhesion of sealer cements to dentin with and without the smear layer. J Endod. 1991; 17: 15-20.
23. van der Sluis LW, Wu MK, Wesselink PR. The evaluation of removal of calcium hydroxide paste from an artificial standardized groove in the apical root canal using different irrigation methodologies. Int Endod J. 2007; 40: 52-7.
24. Nandini S, Velmurugan N, Kandaswamy D. Removal efficiency of calcium hydroxide intracanal medicament with two calcium chelators: volumetric analysis using spiral CT, an in vitro study. J Endod. 2006; 32: 1097- 101.
25. Treewannakul T, Khemaleelakul S. Removal efficiency of calcium hydroxide intracanal medication using various citric acid irrigation techniques. Chiangmai dental journal. 2008; 29: 35-44.