Basic Knowledge and Gene Involvement of Non-syndromic Tooth Agenesis
Tooth agenesis is the most common craniofacial anomaly found in humans. An etiology of tooth agenesis is strongly conditioned by genetic factors. This article reviewed the basis knowledge of tooth agenesis and gene involvement of non-syndromic tooth agenesis. Recently, there were many studies demonstrating the mutant genes involved in non-syndromic tooth agenesis. These results may be suggested to develop early diagnostic tool based on DNA analysis, resulting in more accurate diagnosis and management.
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